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Chapters

Chapter 1 - Introduction to Organic Chemistry: Structure, Bonding, Naming, and Functional Groups

  • How to Actually Survive Organic Chemistry: 5 Habits to Develop Right Away
  • Structure and Bonding
  • Lewis Structures and Formal Charge
  • VSEPR Theory and Molecular Geometry
  • Resonance and Delocalized Electrons
  • Drawing Organic Structures (Structural Formulas)
  • Acid–Base Chemistry in Organic Molecules
  • IUPAC Naming Masterclass
  • Common Functional Groups in Organic Chemistry
  • Isomerism and Stereochemistry
  • Chapter 1 Summary & Key Takeaways
  • Chapter 1 Practice Problems

Chapter 2 - Introduction to Alkanes and Cycloalkanes

  • Reactions of alkanes, including combustion and halogenation
  • Alkane Nomenclature and Properties
  • Isomerism of Alkanes: Chain vs. Positional Isomers
  • Physical Properties of Alkanes and Cycloalkanes
  • Conformational Analysis and Stability
  • Conformational Isomers of Acyclic Alkanes (Newman Projections)
  • Cycloalkane Conformations (Chair, Boat, Ring Flip)
  • Chapter 2 Summary & Reaction Maps
  • Chapter 2 Practice Problems

Chapter 3 - Alkenes and Alkyl Halides (SN1, SN2, E1, E2)

  • Alkene Structure and Nomenclature
  • E/Z and Cis/Trans Alkene Nomenclature
  • Common Alkene Reactions: Electrophilic Additions
  • SN1, SN2, E1, E2: Mechanism Guide
  • Using Alkene Reactions in Synthesis
  • Acid/Base Fundamentals
  • Conjugate Acids and Bases
  • Curved Arrow Conventions in Mechanisms
  • Energy Diagrams and Reaction Coordinates
  • pKₐ Values and Acidity Trends
  • Resonance Stabilization of Conjugate Bases
  • Chapter 3 Summary & Mechanism Review
  • Chapter 3 Practice Problems

Chapter 4 - Introduction to Alkynes

  • Alkyne Structure and Nomenclature
  • Physical Properties of Alkynes
  • Synthesis of Alkynes
  • Reactions of Alkynes
  • Chapter 4 Summary & Reaction Map
  • Chapter 4 Practice Problems

Chapter 5 - Stereochemistry and Chirality

  • Chirality and Enantiomers
  • Assigning R and S Configuration
  • Diastereomers and Meso Compounds
  • Fischer Projections and 3D Representation
  • Enantiomers and diastereomers
  • Optical activity and specific rotation
  • Resolution of Racemic Mixtures
  • Practice with Stereochemical Relationships
  • Chapter 5 Summary & Cheat Sheet
  • Chapter 5 Practice Problems

Chapter 6 - Alcohols and Ethers (and Epoxides)

  • Nomenclature and Properties of Alcohols and Ethers
  • Acid–Base Chemistry of Alcohols and Ethers
  • Synthesis and Reactions of Alcohols and Ethers
  • Chapter 6 Summary & Reaction Map
  • Chapter 6 Practice Problems

Chapter 7 - Amines and Amides

  • Nomenclature and Classification of Amines
  • Structure and Basicity of Amines
  • Synthesis and Reactions of Amines and Amides
  • Diazonium Salts and Aromatic Substitution
  • Biological and Biochemical Relevance
  • Chapter 7 Summary & Comparison Tables
  • Chapter 7 Practice Problems

Chapter 8 - Carbonyl Compounds

  • Carbonyl Compounds - Nomenclature and Properties
  • Acid-catalyzed and base-catalyzed reactions
  • Synthesis and reactions of ketones and aldehydes
  • Imines, Enamines, and Related Derivatives
  • Chapter 8 Summary and Reaction Summary Table
  • Chapter 8 Practice Problems

Chapter 9 - Carboxylic Acids and Derivatives

  • Carboxylic Acids and Derivatives - Nomenclature and Properties
  • Acid-base properties of Carboxylic Acids
  • Synthesis and reactions of carboxylic acids, esters, and anhydrides

Chapter 10 - Spectroscopy

  • Introduction to infrared and nuclear magnetic resonance (NMR) spectroscopy
  • Interpretation of spectra for structure determination

Chapter 11 - Aromaticity and Aromatic Compounds

  • Introduction to Aromatic and anti-Aromatic Compounds
  • Reactivity and Reactions of Aromatic Compounds: Electrophilic Aromatic Substitution
  • Reactivity and Reactions of Aromatic Compounds: Nucleophilic Aromatic Substitution
  • How do I know if a molecule is Aromatic, Antiaromatic, or Not Aromatic?
  • EWG vs EDG: Examples of Electron Withdrawing and Donating Groups

Chapter 12 - Organometallics in Organic Chemistry

  • Introduction to Organometallic Compounds
  • Grignard Reagents, Organolithium Compounds, and Gilman Reagents
  • Transition Metal Catalysis and Coupling Reagents

Chapter 13 - Enols and Enolates

  • Introduction to Enols
  • Enols and Enolates: Mastering Organic Chemistry Reactivity
  • Formation and Reactivity of Enolates
  • Aldol Condensation and Claisen Condensation

Chapter 14 - Carbohydrates

  • Introduction to Carbohydrates
  • Structure and Nomenclature of Carbohydrates
  • Reactions of Carbohydrates

Chapter 15 - Amino Acids

  • The Twenty Amino Acids
  • pKa and Electrical Properties of Amino Acids
  • Amino Acid Synthesis and Protection Reactions

Chapter 16 - Dienes and Diels-Alder Reaction

  • Introduction to Dienes
  • Dienes: Understanding Stability, Resonance Energy, and Kinetic vs Thermodynamic Control
  • Diels-Alder Reaction
  • MISC

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  • STUDY GUIDES

  • Orgo 1
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  • Lessons

  • Intro to Organic Chemistry
  • Naming Alkanes
  • Naming Alkenes
  • Hydrohalogenation Reactions
  • Resonance Structures
  • Bond Types and Orbitals
  • Chirality
  • The Organic Chemistry of Ibuprofen
  • Reaction Library

  • Acid Chlorides
  • Alcohols
  • Alkenes
  • Alkyl Halides
  • Alkynes
  • Amides
  • Aromatics
  • Azides
  • Carboxys
  • Epoxides
  • Esters
  • Aldehydes and Ketones
  • Course Content

  • Chapter 1 - Introduction to Organic Chemistry: Structure, Bonding, Naming, and Functional Groups
  • Chapter 2 - Introduction to Alkanes and Cycloalkanes
  • Chapter 3 - Alkenes and Alkyl Halides (SN1, SN2, E1, E2)
  • Chapter 4 - Introduction to Alkynes
  • Chapter 5 - Stereochemistry and Chirality
  • Chapter 6 - Alcohols and Ethers (and Epoxides)
  • Chapter 7 - Amines and Amides
  • Chapter 8 - Carbonyl Compounds
  • Chapter 9 - Carboxylic Acids and Derivatives
  • Chapter 10 - Spectroscopy
  • Chapter 11 - Aromaticity and Aromatic Compounds
  • Chapter 12 - Organometallics in Organic Chemistry
  • Chapter 13 - Enols and Enolates
  • Chapter 14 - Carbohydrates
  • Chapter 15 - Amino Acids
  • Chapter 16 - Dienes and Diels-Alder Reaction
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